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Has CBD got side effects?

A revision of more than 130 works published in literature reports that also for high dosages of CBD (up to 1500mg/day) no significant side effects are known. In particular no alterations of the major physiological parameters have been demonstrated (e.g. blood pressure and heart-rate) nor any alterations in the psychomo

March 16, 2018
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Image Carousel A revision of more than 130 works published in literature reports that also for high dosages of CBD (up to 1500mg/day) no significant side effects are known. In particular no alterations of the major physiological parameters have been demonstrated (e.g. blood pressure and heart-rate) nor any alterations in the psychomotor functions. The only side effects, occurred however mostly during in vitro studies or on animal models, are: fertility reduction, inhibition of the enzymes involved in hepatic metabolism of pharmacological substances and alterations of the cell viability. In humans the minimal side effects identified in some studies are mainly diarrhoea, fatigue and appetite changes (most frequently a reduction rather than an increase).
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