CBD and Blood Pressure

Table of Contents

The relationship between cannabidiol (CBD) and blood pressure is still being investigated, but some recent studies have shown that one of the main active compounds in the cannabis plant may significantly contribute to lowering blood pressure.

Cannabidiol, when referring to high-quality products, could be beneficial for those suffering from high blood pressure, a common condition that is sometimes asymptomatic but can pose potential health risks.

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CBD and High Blood Pressure: What the Studies Say

Recently, as scientific research has begun to delve deeper into the benefits of the active compounds in the cannabis plant, some studies have drawn attention to cannabidiol (CBD) as a potential substance capable of reducing blood pressure in cases of confirmed hypertension.

Human studies aimed at verifying the potential benefits of cannabidiol (CBD) on blood pressure are still few and relatively recent. In 2017, a study conducted by researchers from the Department of Medicine at the University of Nottingham and the NIHR Oxford Biomedical Research Centre yielded the first encouraging results.

The study involved nine healthy male participants who were administered either 600 mg of cannabidiol (CBD) or a placebo. The volunteers' cardiovascular parameters were monitored and analyzed, revealing that cannabidiol (CBD) reduced systolic blood pressure (the higher number) and stroke volume - the amount of blood pumped by a ventricle - under normal conditions. Similarly, cannabidiol (CBD) also reduced blood pressure when subjects were under stress.

At the time, researchers were not yet able to determine whether this effect of cannabidiol (CBD) was due to a direct cardiovascular action or its anxiolytic and analgesic properties. However, the study by the English researchers was one of the first to call for a better understanding of the potential effect of CBD on hemodynamics: the 'behavior' of blood in circulation.

Indeed, despite numerous studies analyzing the effects of cannabidiol (CBD) in vitro, its effects on hemodynamics in vivo remain unclear. For this reason, another team of researchers from the Royal Derby Hospital Center at the University of Nottingham published a systematic review of all studies conducted to date aimed at verifying the effects of CBD on blood pressure, both in animals and humans.

In the review - published in Frontiers of Pharmacology - a total of 25 studies were considered. The scientists who contributed to this review concluded that, by analyzing the overall data from the studies, cannabidiol (CBD) might be able to reduce blood pressure and heart rate under various stress conditions that had caused an increase.

Based on these findings, the researchers concluded that this action of cannabidiol (CBD) should undoubtedly be investigated further to determine whether its use could be considered to support therapy aimed at reducing blood pressure in cases of arterial hypertension.

CBD, Blood Pressure, and Prevention

Encouraging signs are also emerging from nutritional studies. In 2014, an article was published by Canadian, Australian, and Chinese researchers describing a study on blood pressure and Cannabis sativa L. seeds.

The article, published in the prestigious European Journal of Nutrition, fits perfectly into the 'prevention' approach. While a balanced and proper diet is crucial for maintaining controlled blood pressure, the nutrients provided by hemp seeds have proven to be an excellent ingredient for a healthy diet.

In their research, the scientists fed some mice for periods of 4 and 8 weeks using a protein flour derived from cannabis seeds. At the end of the experiment, they observed a significant decrease in systolic blood pressure (the higher number) compared to the control group mice. The results led the researchers to conclude that cannabis seeds or food products derived from them could be used for the prevention and treatment of hypertension.

High Blood Pressure: The Facts

Hypertension or high blood pressure is a clinical condition where the blood pressure in the arteries is elevated. The heart contracts and exerts pressure - known as systolic blood pressure (the maximum pressure) - which allows blood to flow and deliver oxygen and nutrients throughout our body. Once the contraction is complete, the pressure drops to its lowest value, the diastolic blood pressure (the minimum pressure).

When measuring our blood pressure, we always consider these two values: the minimum and maximum pressure. At rest, normal blood pressure in humans should be equal to or less than 120 mmHg for maximum pressure and less than or equal to 80 mmHg for minimum pressure.

A hypertensive condition is detected when values exceed 140 mmHg for maximum and 90 mmHg for minimum pressure for several days. In our country, considering the broader population group (aged between 35 and 74 years), 50% of men and 40% of women suffer from high blood pressure. This is a concerning statistic, as hypertension significantly increases the risk of developing cardiovascular disease, such as heart attack, kidney failure, or stroke. To lower blood pressure and consequently reduce the risk of cardiovascular diseases, the first step is to adopt a healthy lifestyle, focusing on good nutrition, appropriate physical activity, and completely quitting smoking.

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