Effect of CBD for animals
CBD's effects on animals stem from its interaction with the endocannabinoid system (ECS), a complex cell-signaling network present in mammals. This system plays a crucial role in maintaining homeostasis, influencing various physiological processes including mood, sleep, appetite, and pain sensation [Russo, 2016].
When administered to pets, CBD interacts primarily with two types of receptors in the ECS:
- CB1 receptors: Predominantly found in the central nervous system
- CB2 receptors: Mainly located in peripheral organs and immune cells
Through these interactions, CBD may modulate neurotransmitter release and influence inflammatory responses. This mechanism underlies its potential to address various health concerns in animals, from anxiety to chronic pain.
Species-specific considerations
The effects of CBD can vary between animal species due to differences in metabolism and ECS composition. Dogs, for instance, have a higher concentration of CB1 receptors in their brains compared to humans, potentially making them more sensitive to cannabinoids [Vaughn et al., 2020].
Cats, on the other hand, lack certain enzymes necessary for efficiently metabolizing some plant compounds. This unique physiology necessitates careful dosing and product selection when administering CBD to felines.
For larger animals like horses, CBD's effects may be influenced by their size and specific health concerns. Equine-specific CBD formulations, such as those offered by Enecta, take these factors into account to optimize efficacy and safety.
